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A Popular Sweetener Was Linked to Increased Anxiety in Generations of Mice
(www.sciencealert.com)
this post was submitted on 25 Dec 2023
298 points (89.8% liked)
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1, it's aspartame
2, Mice aren't humans, and routinely, things that happen in mice do not happen in humans. It is not at all indicative of anything and can really only be used as a hint better than nothing for looking into similar effects in humans.
You don't need to change your diet, and you certainly don't need to replace it with sugar.
*But drinking a glass of water from time to time won't kill you either.
Comment paid for Big Aspartame.
Deep Sugar take
I see the Nutrasweet Lobbyists Association is here too!
Big aspertame made that account 6 months ago, posted 1300 unrelated comments, just for this one moment...
The long con!
How much is Big Sugar paying you?
Not enough :(
Considering the patent was held by Monsanto, and all the decades of concerns have been raised by independent researchers but shut down by lobbying...
Well, I mean, who can you trust to not hide that they're making poison if not Monsanto?
Removing all forms of added sugar would probably make everyone feel better. Even minimizing natural sugar intake.
Sugar is terrible, there’s no doubt about it. Artificial or otherwise.
Your lemon curd is full of thickener (egg yolk) and sugar (honey) too.
What thickener did they use? Soy lecithin? That's the same thickener as found in your egg yolks.
What sugar? Just regular sugar? That has a similar glycemic index as honey.
Concentrated lemon juice is just lemon juice without the water. Was there also water in the recipe?
Sounds like your stomach trouble was due to something else. I'm not saying the lemon curd you bought was good quality, but it probably wasn't much different than what you make. And those scary ingredients are the same as the ones that you already use.
Probably the "more than a few" they ate.
Overconsumption leads to health issues? More at 9.
there's little research to show sugar dangers to be more than correlation
fat people eat a lot of sugar. fat people also eat a lot. eating a lot is how you get fat, drinking calories just happens to be a fast track to getting fat. diet soda happens to be physiologically like drinking water. fat people drink diet instead of sugar coke thats already 200-1000 calories of their day GONE with very very minimal change.
then those fat people supplement the lost sugars with more food and they gain weight. then you get studies showing GUYS DIET SODA CAUSES WEIGHT GAIN (in fat people)
but no its not the sugar its not the macros its YOU eating too much and you can eat less to lose weight that's just simple science. body types, "nuance", "bad metabolism". none of that shits real it all stems from shitty dietary choices and lack of muscle.
all of this to say unless theres medical issues or medical intervention your weight and body type is 100% in your control should you choose to take control
How about all the research that shows sugar is addictive AF
self control is a thing everything is addictive in some facet refined sugars just happens to trigger a stronger dopamine response than other things.
but in the end of the day self control is necessary nobody can control you except you. so dont blame sugars addicitiveness for being overweight if you are. its solely an overeating issue.
I feel like you underestimate addiction. "Self control" is what's needed to not start smoking; but it takes something stronger to quit smoking, I think -- a more refined willpower than simple "self control".
And sure, it's something a person could cultivate and train on their own with time and focus. But so are most other things. "Why aren't you good at drawing? All you need to do is practice every day! it's simple."
nicotine is chemically addictive sugar is not.
im a stoner and can assure you the way to quit smoking something that isnt chemically addictive is cold turkey will-power babey. ive taken long breaks when needed with months of straight use 24/7 down to zero for months. its all mind over matter.
im also shredded now because slight caloric deficit and healthy eating is also straight will power mind over matter to consistently eat a slight deficit and well for months. and i do a rigourous calisthenics strength routine consistently to supplement thus I'm quite ripped.
shit even for my cut i completely quit eating added sugars cold turkey i didnt eat any aside from the occasional if i was given something for like 4 months. it was also pretty easy and made occasional sweets taste better and fruits/veggies were gas.
people make shit up as excuses like "ohh im skinny fat its too late", "i dont have time in between my laying down and netflix binge". no body types dont exist. never have never will stop using excuses. if you want to be lazy accept the fact YOU ARE LAZY theres no other excuse than you being lazy. which is chill being lazy is fun sometimes (remember im a stoner) but don't pretend its for some other reason its all on YOU.
everyone thinks oh its too hard i cant do it. but no youre just lazy and weak willed and im not joking. you can do anything if you want to thats the beauty of life. things don't come easy if you see someone doing crazy shit that's probably a conglomeration of years of hard work and dedication. they probably started looking and thinking like you til they woke up.
WAKE UP you dont need to be fat, your metabolism doesn't need to suffer with age, your joints dont need to get worse. all of this happens from a lack of training and poor diet NOT age. age provides the time for your body to degrade you have to prevent that degration. I FUCKING HATE when people say your metabolism will slow down and youll get fat eventually. bitch no ill never be like you.
also finally, i am a drug addict i know about addiction trust me. I've quit some shittier things it takes effort but in the end of the day still its on YOU to quit nobody can quit for you.
I'm not sure what you mean by this. If you mean a sugar addiction is more like a gambling addiction than a nicotine addiction, I don't think that's the case; you can find studies that claim sugar addiction is "opiate-like". There are also some sensational claims like "sugar is more addictive than cocaine", though that seems like more of a stretch to me.
I'm glad to hear you are in great shape, and it's clear you tie a lot of self worth to physical fitness. But I would caution you not to use that as an excuse to look down on others.
Of course sugar is addictive as fuck - you would literally die without it.
Absolutely nothing wrong with a diet high in fruit and veg, both of which contain significant amounts of sugar.
You are correct, the caveat "added sugar" or added sweetener in this case is the important bit.
Fructose doesn't have the same health effects of sucrose for some reason and the sugar you eat in fruit and veg come with fiber which helps keep our blood sugar from spiking.
I was shocked to learn that dates, which are basically candy, have a pretty reasonable glycemic index.
Except that guy wrote:
Which precludes fruit and a good deal of veg.
Fair point. Have a happy new year!
That's because fructolysis has a slightly different pathway and fate as compared to glycolysis, which results in far lower efficiency of conversion. Meaning glucose gets converted into more calories than fructose does.
Fascinating! It is astounding to me how we know some of this stuff and how there is so much we have left to discover
Fruits make me just as sick as any other source of sugar. Fruit is just candy in a natural wrapper.
Not to mention that the gene pool of these lab mice is super small. Source: my brother is a PhD biochemist and lectured me often on this shit when I said, "hey, look at this study!"
The small gene pool is done on purpose. The mice are supposed to be as close to clones as possible so that you can have control populations and be confident that the results weren't affected by certain genes and mutations in the test population.
The size of the gene pool isn't really an issue though because they can be bred however it's required for tests. They have quite a lot of control over the genetics of those lab mice.
Testing for a cure for diabetes? They can produce mice that are almost guaranteed to develop diabetes that you can then try to cure.
Such a small groups are fine for initial investigation, they have enough of a size to be acceptable statistically for most of the performed studies. I don't think they'd get approval from ethical committee overseeing animal experiments without initial study like this to conduct something on very high groups.
I am a relatively recent transplant from the red place, I can tell I ain't in Kansas anymore, actual good information being up voted so cool.
Aspartame is, because of all the claims against it, the single most studied food substance known, and it seems to somehow keep coming okay. There are a lot of studies with really bad methods that were a smear job attempt but science doing what it does they were labeled for what they are and disregarded. Is it possible to be allergic and a reaction to be anxiety sure, but that is not on the food.
Guarantee the study also states that you have to consume an ungodly amount of it too...
News reports grab on to stuff like this all the time. Like what they did with safrole.
The article actually states how much. 15% of the daily recommended amount.
There's a daily recommended amount for mice? Or was that 15% of the recommended amount for humans, which would be massive for mice?
15% of humans recommended amount. It's in the article.
Actually no, the keyword is equivalent, so adjusted for body weight.
Ah I think you're right.
So 15% for a 60 kilogram human, on the lower end, would be the daily recommended amount for a 9 kilogram creature. A mouse weighs around 0.025 kilograms. So, that amount for the mice is for something 360 times larger.
Obviously it's more complicated than that with differing metabolisms and the like, but as a rough estimate, wow. That's a lot.
I'm baffled by your willingness to elaborate at length about this, but not read the article where this is explained. Misinforming everyone in the process.
It's the equivalent of the human daily dose. So adjusted for body weight. Loosely translated, it would be 15% of the daily recommended dose for mice.
I stand corrected! That's a ridiculously small amount!
Just in case you missed it, we discussed below that that's the 15% daily recommended amount for a human. That they gave to the mice. A creature several hundred times smaller.
So you were right in the first place.
No, it's the equivalent dose.
Can you cite your sources? This excerpt from the published article suggests you're wrong: