this post was submitted on 18 Feb 2025
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Science Memes

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[–] [email protected] 50 points 3 days ago* (last edited 3 days ago) (7 children)

Xenon is a drug?

Drugs.com calls it "physiologically inert" with some anaesthetic effects at high doses. Most of the coverage is about Xe-133 radiopharmacology and not what most people would think of as a "drug". Is there more to the story?

https://www.drugs.com/pro/xenon-xe-133-gas.html

[–] threelonmusketeers 17 points 3 days ago

Is there more to the story?

Not that I'm aware of. I'm assuming Tom was referring to its anaesthetic effects, which I don't think have been widely studied.

[–] [email protected] 11 points 3 days ago (1 children)

iirc it's a dissociative.

I remember Hamilton's pharmacopeia doing an episode on it. Apparently it is/was popular in Russia.

Here's a video of Hamilton doing some: https://youtu.be/dj25HO48Gxw

[–] anomnom 2 points 3 days ago

Is it me or is he just slightly asphyxiated after the first breath?

We messed with sulfur hexaflouride a while back, and it’s kinda difficult to exhale it all without putting your head between your knees and breathing hard.

[–] [email protected] 7 points 3 days ago (1 children)

It works by dispersing oxygen from the blood. The lack of oxygen gives you a high. Which is can turn deadly if you don't unhook when passing out.

[–] [email protected] 7 points 3 days ago (1 children)

Isn't that the same as Nitrogen, like [email protected] said? That doesn't sound like there's any unique mechanism to Xenon.

[–] [email protected] 1 points 2 days ago
[–] Tar_alcaran 9 points 3 days ago

At the worst, you can use it like people use nitrogen. To get a very brief high from lack of oxygen (and then possibly die)

[–] [email protected] 3 points 2 days ago (1 children)

Don't listen to the people who say it works by displacing oxygen. It would never be used as a general anesthetic if that was the mechanism of action.

Xenon has been used as a general anesthetic, but it is more expensive than conventional anesthetics.

Xenon is a high-affinity glycine-site NMDA receptor antagonist.[155] However, xenon is different from certain other NMDA receptor antagonists in that it is not neurotoxic and it inhibits the neurotoxicity of ketamine and nitrous oxide (N2O), while actually producing neuroprotective effects.[156][157] Unlike ketamine and nitrous oxide, xenon does not stimulate a dopamine efflux in the nucleus accumbens.[158]

Xenon has a minimum alveolar concentration (MAC) of 72% at age 40, making it 44% more potent than N2O as an anesthetic.[164] Thus, it can be used with oxygen in concentrations that have a lower risk of hypoxia.

https://en.wikipedia.org/wiki/Xenon

[–] [email protected] 2 points 2 days ago

I didn't think to check Wikipedia for pharmacology info haha. Thanks.

[–] [email protected] 4 points 3 days ago

oh, so it's a "medicine drug"...

[–] [email protected] 2 points 2 days ago

Yeah. If you spray it on a hammer and hit someone's head with it, it knocks them right out.

[–] [email protected] 23 points 3 days ago (2 children)

Man explosion&fire/extractions&ire are some of the best channels on Youtube, love that dude

[–] [email protected] 2 points 2 days ago

G'DAY AND WELCOME TO EXPLOSIONS AND FIIIIIRE!!! I love nothing in the world more than ex&f

[–] [email protected] 3 points 3 days ago (1 children)

I'm reading all these comments in his voice.

[–] threelonmusketeers 1 points 2 days ago

So am I, mate!

[–] Imgonnatrythis 22 points 3 days ago (1 children)

Either way, as long as I get to drink my lightly processed urine through a special straw in my jumpsuit, dammit I'm in.

[–] threelonmusketeers 12 points 3 days ago

"Lisan al Gaib!"

[–] [email protected] 17 points 3 days ago

https://youtube.com/@explosionsandfire if he releases it soon and you want to watch it instead of just seeing the post where he demos the title card

[–] [email protected] 6 points 2 days ago (1 children)

Is xenon actually that rare? I thought it's always used whenever something needs an ultra stable environment like enclosed data centers and sealed storage/vaults.

[–] threelonmusketeers 2 points 2 days ago (1 children)

Yeah, compared to other noble gases, it's pretty rare, and we don't produce very much. If I recall correctly, the 900 kg loaded on the Psyche spacecraft last year represented about 10% of the world production.

[–] [email protected] 1 points 2 days ago

That doesn't make it rare. It's just a byproduct that is produced in large enough quantities for other uses without specifically cracking air to produce it rather then oxygen and nitrogen.

[–] [email protected] 6 points 3 days ago

Xenon are an advanced robotic faction in the X universe, so Xenon for space travel checks out

[–] [email protected] 3 points 2 days ago

Love me some Explosions and Fire