this post was submitted on 14 Nov 2024
849 points (98.8% liked)

Science Memes

11479 readers
1210 users here now

Welcome to c/science_memes @ Mander.xyz!

A place for majestic STEMLORD peacocking, as well as memes about the realities of working in a lab.



Rules

  1. Don't throw mud. Behave like an intellectual and remember the human.
  2. Keep it rooted (on topic).
  3. No spam.
  4. Infographics welcome, get schooled.

This is a science community. We use the Dawkins definition of meme.



Research Committee

Other Mander Communities

Science and Research

Biology and Life Sciences

Physical Sciences

Humanities and Social Sciences

Practical and Applied Sciences

Memes

Miscellaneous

founded 2 years ago
MODERATORS
 
all 49 comments
sorted by: hot top controversial new old
[–] [email protected] 69 points 1 month ago (1 children)

I fix software on these things! No one ever quite gets what I do for work, it's nice to run across in the wild.

I feel seen lol

[–] clay_pidgin 25 points 1 month ago (2 children)
[–] phdepressed 53 points 1 month ago (6 children)

Top left is a thermal cycler. Basically it heats and cools samples at a given rate. This is primarily used for generic PCR, and certain enzymatic reactions. Top right is the fancier version of this, it is for qPCR, so it can do the heating and cooling and has a laser/detector for the dye or probe that reacts to generating more dna with each PCR cycle so you can quantify approximately how much of the target DNA you had.

Bottom right is a luminex. This uses detection of fluorophore signals to measure multiple analyates, usually different proteins.

Idk what bottom left is.

[–] [email protected] 16 points 1 month ago (1 children)

Wow, I know some of those words.

[–] [email protected] 24 points 1 month ago* (last edited 1 month ago)

Allow me to translate:

Top left is a thermal cycler. Basically it heats and cools samples at a given rate. This is primarily used for magic. Top right is the fancier version of this, it is for qMagic, so it can do the heating and cooling and has a magic detector for magic components that reacts to magic happening so you can quantify approximately how much magic is going on in the beige box.

Bottom right is a luminex. This uses detection of magic signals to measure magic.

Bottom left is the beige box where magic happens.

[–] [email protected] 9 points 1 month ago (1 children)

Top left is the CFX96/384, which is also a qPCR instrument.

Bottom left is the 3500 Genetic Analyzer, as someone identified. It's used for sanger sequencing I believe. My last lab had one but I was never trained on it.

[–] phdepressed 5 points 1 month ago (1 children)

I thought it was just their T100, the CFX96s I've used don't have the touchscreen but yeah the bigger "lid" does look like for the CFX.

[–] [email protected] 2 points 1 month ago

The bases and hot blocks are interchangable with that series. We recently upgraded to the Opus but our previous CFX96 had the T1000 touch base.

[–] [email protected] 5 points 1 month ago

This guy sciences.

Also username checks out.

[–] Fuck_u_spez_ 3 points 1 month ago

I know nothing about this kind of lab equipment but Google says the bottom left device is a human DNA sequencer, ABI model 3500.

[–] clay_pidgin 3 points 1 month ago

Thank you, they sound really specialized!

[–] [email protected] 7 points 1 month ago (1 children)

Some kinda lab work, maybe blood chem or urinalysis. I should clarify that since I'm a software person I don't even know what they do, really, I just fix it when they stop transmitting lab test results to the database.

[–] [email protected] 5 points 1 month ago

Getting the magic back to the magic analysis database got it

[–] [email protected] 59 points 1 month ago
[–] [email protected] 47 points 1 month ago (1 children)
[–] [email protected] 3 points 1 month ago

beige box where the magic happens

[–] [email protected] 45 points 1 month ago

You'll need a PhD to be allowed to push the "on" button though.
And then go back to the office to write grant applications for a month.
To buy the next beige box.

[–] [email protected] 42 points 1 month ago (5 children)

This used to be IT in the early 2000s

Beige as far as the eye could see (in a data centre)

[–] neidu3 14 points 1 month ago (2 children)

Yeah, I came here to air my hypothesis that lab hardware trends lag behind consumer computers by about 25-30 years.

[–] [email protected] 8 points 1 month ago (1 children)

Are you saying there used to be woodgrain lab hardware?

[–] neidu3 7 points 1 month ago

There definitely was. I've seen it.

[–] [email protected] 6 points 1 month ago (1 children)

So it's almost time for teal, orange et other fun colors, mixed with translucent plastic lab équipement?

[–] neidu3 5 points 1 month ago

In 5 years hardcore researchers will be modding their lab equipment and installing plexiglass glass sides. Just like I did to my PC in 1999-2000ish

[–] [email protected] 9 points 1 month ago

Nowadays it's a lot more of dark mode, which is a shame (especially since our software still doesn't have it)

[–] [email protected] 6 points 1 month ago (1 children)

I'm waiting for it come back in to style. I've pitched getting beige racks with this on the side https://en.m.wikipedia.org/wiki/Jazz_(design)

[–] [email protected] 1 points 1 month ago

woah dude, that's far out

[–] [email protected] 5 points 1 month ago (1 children)

Honestly, I think it was so ugly it was beautiful.

[–] [email protected] 5 points 1 month ago (1 children)

There is also this particular tone of light brownish green which is on so many industrial tools like drill presses, table top saws and so on. I kinda dig it

[–] [email protected] 2 points 1 month ago

Ooh, never thought of that as so ugly it's pretty but I can kinda see it now

[–] [email protected] 1 points 1 month ago (2 children)

Were we still using 3.5” floppies in the early 2000s?

[–] [email protected] 2 points 1 month ago (1 children)

Oh yes, I was using a 3.5" floppy disk drive with a USB connector in 2007 to kick off imaging on desktop machines as no one could get the ghost boot server working.

[–] [email protected] 1 points 1 month ago (1 children)

Why not just use a thumb drive at that point?

[–] [email protected] 2 points 1 month ago

I can't remember specifically, I think it might have just been that the ghost image on the floppy was confirmed to work, and all the desktops were allowed to boot from floppy already and not necessarily via USB.

[–] [email protected] 25 points 1 month ago (1 children)

But do you have magic box where the beige happens?

[–] [email protected] 18 points 1 month ago

That's at home Depot.

[–] [email protected] 10 points 1 month ago (2 children)

We had a bright orange magic box that was connected to a beige windows 95 box that you were never allowed to turn off because nobody knew if it would survive a reboot and there was no software for the orange box for a more modern setup. Almost felt an like arcane ritual, typing in the command lines to get it to work.

[–] [email protected] 2 points 1 month ago (1 children)

Could honestly try a virtual machine or an emulator at that point. Would be worth a shot.

[–] [email protected] 2 points 1 month ago

My workplace was still using DOS machines (386s) in 2015 to format letters. It couldn't be emulated as the critical component was an ISA card

One of the pieces of work I worked on was diverting the data stream aimed at that letter system and translating it to go via our more modern correspondence system

[–] can 2 points 1 month ago (1 children)
[–] Trollception 3 points 1 month ago

Probably plugged into some sort of UPS or the building has backup power.

[–] [email protected] 9 points 1 month ago

Most of ours used to be white!

[–] [email protected] 9 points 1 month ago (1 children)

Which beige box will turn me into a femboy?

[–] [email protected] 9 points 1 month ago (1 children)
[–] [email protected] 4 points 1 month ago

Leave the bottle...

[–] [email protected] 3 points 1 month ago

Available in the Thermo Fisher catalog for $39,900,800.00 each.

[–] [email protected] 1 points 1 month ago

Johnny Ives would have gotten rid of all those nasty bevels.

[–] [email protected] 1 points 1 month ago

Science was cooler when you had to use a screwdriver.

(This ad paid for by Demon Core Ltc.)