Omega 3-6-9 fatty acids. There's been a fair amount of research done on its role in mitigating ADHD, specifically. I take them and notice a decline in mood and overall presence of mind when I've forgotten to take my pills for a while.
this post was submitted on 01 Jun 2025
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ADHD
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Interesting, thanks for the paper link, I'll have to come back to that!
Could you recommend your supplement? There are a LOT out there.
I get whatever's on sale.
Big props for the PubMed link, hard to take anything else seriously.
I believe in good sources. Thanks for noticing ~
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The best supplement is regular exercise imo
Added. It’s not really a supplement, but improving one’s health can do a lot for stress and sleep. That can take some of the edge off the related ADHD issues.
I mean, chelated magnesium helps take the edge off of Adderall but no, I doubt you'll ever find anything otc that is effective as something prescribed.
I wouldn’t expect any supplements, vitamins, or similar to be as effective, but to use your words, maybe some things that help “take the edge off.”
Well, the CM takes the edge (jitters) off of the adderall. The supplement does zero for ADHD. There aint a lot of options aside from stimulants. Soooo 500mg+ of caffeine in whatever form is your preference?
Creatine monohydrate helped for me. It's usually taken by athletes and gym-goers but there's a study saying that it may improve short term memory and intelligence/reasoning
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I find a combination of St. John's Wort and Lion's Mane Extract help with my mood and focus.
Added lion’s mane. Which one do you use for what?
Lion's Mane is for focus. St John's Wort is for mood but as someone else has correctly commented, SJW should not be used if you are already taking any prescription anti-depressants as it can cause seretonin syndrome.
FYI, St John's wart can affect serotonin, which can be dangerous if you're on anti depressants.
It can also reduce the effectiveness of hormonal birth control.
Lions mane extract seemed to help me, before I knew I had ADHD. Just seemed like when I had it regularly I had less brain fog. I used a few ml every morning in stone water.
I stopped using it because it seemed pricey, and I only bought it from one guy at the farmers market because I know a lot of commercially available supplements dont have what they say they do in the US.
I should try to find another good source to see if it helps now that I have other things as well.
Also black coffee but fresh roasted / fresh ground specialty coffee seems to help way more. Grocery store coffee gives me heartburn
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Magnesium glycinate. Made every difference in the world for me - I still need my meds to perform at my best, but I can muddle through without them with magnesium and a good night of sleep
I used take other forms of Magnesium, but recently found Glycinate has made a massive improvement in my sleep.
Best sleep I've had in years.
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NAC - N-acetyl-cysteine. Psychiatrist recommended it for weaning myself off a THC dependency, but after reading a few PubMed-available research papers I found data supporting further research into its effects on ADHD.
Additionally, I kept researching in an attempt to improve brain fog and sleep issues I suspect are from long COVID. I found studies indicating NAC combined with guanfacine may help those symptoms.
I've found better results from 600mg NAC (standard daily dose is 1200mg) taken three times a day, and started 1mg guanfacine twice a day recently with plans to increase to 2mg twice a day in a week or two.
I would love to share the NIH papers with anyone interested. Educating yourself about your condition and its particular manifestation will get you far with an invested care team. I'm headed to bed bit will reply to any and every person interested in the research tomorrow morning.
The message I sent to my psych two days after she recommended NAC contained inline citations referring to the papers I had linked at the bottom. That due diligence communicated my dedication not only to my own care, but also to my dedication and respect for knowledge.
Don't take random supplements recommended to you on the internet. Discuss their use with a doctor or, barring that, ground your decisions in science.
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I hyper focused on my gut microbiome and the results are very interesting. No more anxiousness, amazing sleeps, and way better ment focus. Almost never forget things now. There is a lot of scientific support here too as the microbiome really does play a large role in our mental state.
It sounds like you’re improving your overall health. That’s always valuable.
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Adding my own, and I just started these a month or so ago so I’m not entirely sure that the effects are correct, but they seem to be helping slightly.
Magnesium Glycinate
L- Threonate (1/2 dose, found it made me sleepy too early at full dose)
D
Standard multivitamin (no “extreme” values, everything is 100% or less)
Omega 3
I have absolutely noted a better sleep. Far less mind-churning time when trying to fall asleep. I would guess a little less brain fog and stress, but I don’t know if memory is any better. Having a little less anxiety does help a bit, because you’re not focusing on the stressful thing and have a chance to remember what you were supposed to. The last three I was taking anyway for general health reasons. The magnesium and L-Threonate I picked up just to see if they might help with ADHD.
Magnesium, D and Omega 3 are, as far as I know, all things where you gain a lot if you have a deficit that they compensate, otherwise nothing.
I too took shots in the dark, as I didn't find a doc who was willing to do some more tests. But recently I found out that in some countries, you can just go to a lab directly and they'll draw the blood.
Currently on Magnesium, too (Carbonate though), paused the D due to long times in the sun recently, Omega 3 currently through engineered staple foods & rape oil.
Added.
It’s super hard to “OD” on D, so probably not much need to stop it other than just not consuming the $ as fast. Added to the list.
afaik, 25µg D3 in combination with 20µg K2 should cover it in theory, even when there is hardly any natural source. Some supplement nerds have some reasoning for 100µg, which is near the upper bound of "harmless".
Much more than that can be quite dangerous, though! One drop of the stuff I have is 25, so it's not just theoretical.
EDEKA are the ones where too much is harmful.
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