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It's possible to bioengineer yeast to turn sugar into morphine.
Unfortunately, I am allergic to morphine, wake me up when they can turn sugar into Dilaudid.
Or better yet, morphine into fully baked sugar cookies.
The proof of concept was done with Hydrocodone synthesis. It seems like they have the ability to tweak the yeast to complete complex synthesis to end product. I would bet Hydromorphone would be possible.