Reports so far indicate that the Yak-52 carries a gunner in the rear cockpit, who takes aim on drones using some kind of infantry weapon, likely a light machine gun.

Prop planes engaging in gun combat hasn't been much of a thing since WW2, aside from some sporadic incidents using World War-era hardware:

https://www.wearethemighty.com/mighty-history/the-last-dogfight-between-propeller-airplanes-happened-in-central-america/

The last dogfight between propeller airplanes happened in Central America

In 1969, Honduras and El Salvador fought a brief but explosive war that lasted 100 hours.

But it may make a lot of sense in the context of countering UAVs.