I've hosted mine for years on my own bare metal Debian/Apache install and 28 is the first update that has been a major pain. I've had the occasional need to install a new package to enable a new feature, or needed to add new/missing indices to the database, but the web interface literally tells you how to do those things, so they're not hard.
28 though broke several of the "featured" apps that I use regularly, like "Retention". It also introduced some questionable UI changes that they had to fix with the recent .1 update. I'll get occasional errors when trying to move or delete files in the web interface and everything. 28 really feels like beta software, even though we're a point release in and I got it from the "stable" update channel.