Asklemmy

43956 readers

842 users here now

A loosely moderated place to ask open-ended questions

Search asklemmy 🔍

If your post meets the following criteria, it's welcome here!

Open-ended question
Not offensive: at this point, we do not have the bandwidth to moderate overtly political discussions. Assume best intent and be excellent to each other.
Not regarding using or support for Lemmy: context, see the list of support communities and tools for finding communities below
Not ad nauseam inducing: please make sure it is a question that would be new to most members
An actual topic of discussion

Looking for support?

Looking for a community?

Lemmyverse: community search
sub.rehab: maps old subreddits to fediverse options, marks official as such
[email protected]: a community for finding communities

~Icon~ ~by~ ~@Double_[email protected]~

founded 5 years ago

MODERATORS

[email protected]

274

What are some things you can/should cheap out on? (lemmy.world)

submitted 10 months ago by [email protected] to c/[email protected]

346 comments fedilink hide all child comments

I often hear, "You should never cheap out on a good office chair, shoes, underpants, backpack etc.." but what are some items that you would feel OK to cheap out on?

This can by anything from items such as: expensive clothing brands to general groceries.

you are viewing a single comment's thread
view the rest of the comments

[–] [email protected] 21 points 10 months ago* (last edited 10 months ago) (3 children)

Generics are required to be as efficacious as name brand in the US.

I do not understand your point on encapsulation and the form of the drug. Name brands can have different encapsulations and forms within their own line. That has nothing to do with it being name brand vs. generic.

[–] Cheers 5 points 10 months ago

Was confused by their post too. Not to mention, generics typically say that they're trying to replicate xyz extended release or xyz extra strength.

[–] [email protected] 2 points 10 months ago

Generics are required to be as efficacious as name brand in the US.

Let me introduce you to the way the FDA actually works.

[–] [email protected] 1 points 10 months ago* (last edited 10 months ago)

As someone who takes Adderall daily and has for many years, I can tell you the Teva brand generics work very well while the malinkrokdt (sp?) in the same dosage do almost nothing, and I crash very fast and need a nap in the afternoon and have to go to sleep early.

Conversely, I got some random Indian-HQ brand from Walmart many years ago (a pink tablet) that kept me up for 3 days. I was begging God for sleep. Placebo or nocebo my ass. Pretty sure someone "accidently" added a methyl group and was overly gracious with the dosage.

The book Bottle Of Lies goes into this much deeper. https://www.npr.org/sections/health-shots/2019/05/12/722216512/bottle-of-lies-exposes-the-dark-side-of-the-generic-drug-boom

But it's also noticable in OTC meds. If you get real, severe inflammatory pain (not 'oh I have le headache'), buy a bottle of ibuprofen from the local dollar store and then buy brand-name Ibuprofen from a big box store, and blind test yourself.

(I may be misremembering the specifics on this part) Generics can only be 80% similar to the brand name in formulation, and often times they use fillers and binders that aren't as good as the formulation created by the R&D department of PharmaCo.

I'm not saying generics do nothing, I'm just saying my boss asks me what's wrong when I can't get my Tevas filled and have to use another manufacturer.