this post was submitted on 06 Dec 2023
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[–] [email protected] 2 points 11 months ago* (last edited 11 months ago) (2 children)

Naltrexone

I will start with naltrexone, which can help people who have difficulty regulating their drinking have a more natural and sustainable relationship with alcohol should they choose to not cut it out of their lives entirely.

I consider this the closest thing to a "cure" for drinking problems but it required discipline and it doesn't prevent actual impairment, only the buzz and liking/compulsion to keep overdoing it that day/session

[–] [email protected] 2 points 11 months ago (2 children)

It's also used for opioid abuse disorders. Truly a miracle drug.

[–] [email protected] 1 points 11 months ago* (last edited 11 months ago)

I want to more rigorously experiment with it and other compulsive things I have challenges with, it seems the opioidergic system mediates liking and the compulsive attachment that flows from that so I'm curious to what extent its effect is extensible to other problematic habits, chemical or otherwise

[–] [email protected] 1 points 11 months ago* (last edited 11 months ago) (1 children)

Can you expand on its actual use (like Vivitrol?) My understanding is its primarily used to treat alcoholism/AUD but maybe Vivitrol is used for both...

[–] [email protected] 2 points 11 months ago (1 children)

I can't comment on it personally, no, I've just heard and read about it some.

This article, for example, mentions dosage guidelines: https://www.mayoclinic.org/drugs-supplements/naltrexone-oral-route/proper-use/drg-20068408

[–] [email protected] 1 points 11 months ago* (last edited 11 months ago)

[not snarky ;)] Pretty sure my understanding is correct, I've read about it before

[–] [email protected] 2 points 11 months ago

Low Dose Naltrexone is amazing for all kinds of chronic pain and inflammation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962576/