The instance seems to be mostly right wing trolls. I know defederating is unpopular but I don't think much is to be lost in this case and it can save the mods some headaches.
Edit: the response on exploding-heads.com to my reporting of transphobia. Courtesy of the "second in command"
They know they're acting like dicks, they're openly proud and revel in it and it's a core, fundamental part of who they are. Hateful bigots such as them don't have any interest in changing who they are or improving their behaviour, they will just shift the goalposts and double down every time they are challenged. It's been proven time and time again that they are not looking to be reasonable.