I've used LaTeX, Markdown, and Typst extensively. So far as I can tell, the only benefit this currently has over Typst is that it can output to HTML, And Typst is currently working on that.

Math formatting in LaTeX is awful compared to Typst. Markdown and quarkdown just copy LaTeX's math formatting.

On the readme for quarkdown, it compares many of the popular typsetting software (QD, MD, LaTeX, Typst, ...). It says Typst has a higher learning curve than QD. I would argue that this is only true if you're expecting LaTeX. If you have any experience with programming, this is just not the case.

In the demo, it shows examples of scripting, and running calculations in the document. Comparing how to do scripting in QD vs Typst, these have the same result:

Typst:

#{2*3}

QD

{2}::multiply {3}

6

The syntax for doing math is just more concise with typst.

This is an interesting project, but typst will remain my preferred typsetting software.