If you are on the latest driver, yup, that's the fix.
Apparently the enablement package reintroduces the bug where custom settings are always reset on startup... just letting you guys know this. Use ViveTool if you absolutely need your settings to be kept.
https://community.amd.com/t5/drivers-software/adrenaline-resetting-to-defaults-every-reboot/m-p/634243#M181135
We need to push Microsoft to fix this AGAIN... -3-
Cheers!
If you are on the latest driver, yup, that's the fix.