this post was submitted on 07 Jul 2023
22 points (100.0% liked)

Medicine

1084 readers
1 users here now

This is a community for medical professionals. Please see the Medical Community Hub for other communities.

Official Lemmy community for /r/Medicine.


[email protected] is a virtual lounge for physicians and other medical professionals from around the world to talk about the latest advances, controversies, ask questions of each other, have a laugh, or share a difficult moment.

This is a highly moderated community. Please read the rules carefully before posting or commenting.



Related Communities

See the pinned post in the Medical Community Hub for links and descriptions. link ([email protected])


Rules

Violations may result in a warning, removal, or ban based on moderator discretion. The rule numbers will correspond to those on /r/Medicine, and where differences are listed where relevant. Please also remember that instance rules for mander.xyz will also apply.

  1. Flairs & Starter Comment: Lemmy does not have user flairs, but you are welcome to highlight your role in the healthcare system, however you feel is appropriate. Please also include a starter comment to explain why the link is of interest to the community and to start the conversation. Link posts without starter comments may be temporarily or permanently removed. (rule is different from /r/Medicine)

  2. No requests for professional advice or general medical information: You may not solicit medical advice or share personal health anecdotes about yourself, family, acquaintances, or celebrities, seek comments on care provided by other clinicians, discuss billing disputes, or otherwise seek a professional opinion from members of the community. General queries about medical conditions, prognosis, drugs, or other medical topics from the lay public are not allowed.

  3. No promotions, advertisements, surveys, or petitions: Surveys (formal or informal) and polls are not allowed on this community. You may not use the community to promote your website, channel, community, or product. Market research is not allowed. Petitions are not allowed. Advertising or spam may result in a permanent ban. Prior permission is required before posting educational material you were involved in making.

  4. Link to high-quality, original research whenever possible: Posts which rely on or reference scientific data (e.g. an announcement about a medical breakthrough) should link to the original research in peer-reviewed medical journals or respectable news sources as judged by the moderators. Avoid login or paywall requirements when possible. Please submit direct links to PDFs as text/self posts with the link in the text. Sensationalized titles, misrepresentation of results, or promotion of blatantly bad science may lead to removal.

  5. Act professionally and decently: /c/medicine is a public forum that represents the medical community and comments should reflect this. Please keep disagreement civil and focused on issues. Trolling, abuse, and insults (either personal or aimed at a specific group) are not allowed. Do not attack other users' flair. Keep offensive language to a minimum and do not use ethnic, sexual, or other slurs. Posts, comments, or private messages violating Reddit's content policy will be removed and reported to site administration.

  6. No personal agendas: Users who primarily post or comment on a single pet issue on this community (as judged by moderators) will be asked to broaden participation or leave. Comments from users who appear on this community only to discuss a specific political topic, medical condition, health care role, or similar single-topic issues will be removed. Comments which deviate from the topic of a thread to interject an unrelated personal opinion (e.g. politics) or steer the conversation to their pet issue will be removed.

  7. Protect patient confidentiality: Posting protected health information may result in an immediate ban. Please anonymize cases and remove any patient-identifiable information. For health information arising from the United States, follow the HIPAA Privacy Rule's De-Identification Standard.

  8. No careers or homework questions: Questions relating to medical school admissions, courses or exams should be asked elsewhere. Links to medical training communitys and a compilation of careers and specialty threads are available on the /r/medicine wiki. Medical career advice may be asked. (rule is different from /r/Medicine)

  9. Throwaway accounts: There are currently no limits on account age or 'karma'. (rule is different from /r/Medicine)

  10. No memes or low-effort posts: Memes, image links (including social media screenshots), images of text, or other low-effort posts or comments are not allowed. Videos require a text post or starter comment that summarizes the video and provides context.

  11. No Covid misinformation, conspiracy theories, or other nonsense

Moderators may act with their judgement beyond the scope of these rules to maintain the quality of the community. If your post doesn't show up shortly after posting, make sure that it meets our posting criteria. If it does, please message a moderator with a link to your post and explanation. You are free to message the moderation team for a second opinion on moderator actions.

founded 2 years ago
MODERATORS
top 6 comments
sorted by: hot top controversial new old
[–] [email protected] 5 points 1 year ago* (last edited 1 year ago) (2 children)

As I said over on [email protected]

This is super cool! And they were able to make another major chemical precursor too. I see the yield for ibuprofen is only 64% but I have to assume that’s there room to optimize that reaction scheme to generate higher yields!

I would love to see the full synthesis process as well as reaction conditions, but like everyone else who leaves academia I lost access to journals after finishing my grad program.

[–] [email protected] 4 points 1 year ago* (last edited 1 year ago) (1 children)

I noticed the PDF is available if you simply throw the article title into scholar.google.com .

Edit: Wait, it is just open-access. https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cssc.202300670

[–] [email protected] 3 points 1 year ago

That’s awesome! Kudos to the European Chemical Society, ACS loves their paywall

[–] [email protected] 3 points 1 year ago

but like everyone else who leaves academia I lost access to journals after finishing my grad program.

I still have my academic account but the sci-hub experience is so much easier that I just use that anyway.

[–] [email protected] 5 points 1 year ago* (last edited 1 year ago) (1 children)

They successfully converted β-pinene into two everyday painkillers, paracetamol and ibuprofen, which are produced on ~100,000 ton scales annually.

At first I couldn't believe that we make 100,000 TONS of paracetamol (acetaminophen) a year.

1E5 tons per year / 6E9 people on earth = 17 grams per person per year

My tylenol pills are 500mg, and ~34 pills per year seems about right.

Wow. At a density of 1.3 g/cm^3 that's about half an olympic swimming pool of acetaminophen a year.

[–] [email protected] 2 points 1 year ago* (last edited 1 year ago)

Nice breakdown. Maybe update your stats a little, we're at nearly 8e9 people on the planet. Doesn't change your conclusion much.

load more comments
view more: next ›