this post was submitted on 27 Sep 2023
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Up until now, I've only gotten the Pfizer vaccines. And while I've reacted to them, it was never particularly bad. Light muscle aches and some fatigue were basically it. Worst was the second one - I could feel my hair follicles and eyelids with that one.

But the Moderna one seems to be quite the beast.

When I found out I could get the new Moderna, I was excited, since I've heard that mix-and-match is probably the strongest immunity you can get. And I figured it wasn't going to be that bad when after several hours, I only had some light fatigue.

But today has been awful. Consistent fever around 102.3, chills, headache, nausea, whole-body aches, and ludicrous levels of exhaustion. I've been utterly useless.

Is this what Moderna vaccines have been like all along? I'll take it over contracting COVID-19, definitely... but ouch. It's hurting me plenty.

Next morning update: Chills are gone, fever seems to be gone, muscle aches aren't entirely gone, but they're fading. All in all, 10/10 would feel like shit for a day again to help stop the spread of a dangerous disease.

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[–] [email protected] 36 points 1 year ago (4 children)

I think the moderna dosing is still double the pfizer dose. So I think it's always caused a larger immune response. Ibuprofen will deal with most of those symptoms if you're really not feeling good.

[–] PurpleTentacle 10 points 1 year ago

I believe one can't 1:1 compare the dosage, Pfizer's MRNA was supposed to be a little more stable and hence less of it was needed. But, yeah, Moderna's dosage is higher.

I've gotten both over the years and Moderna always knocked me out harder, but never like OP. Symptoms have always been medium to strong fatigue and at most a mild headache.

I haven't gotten the new booster yet.

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[–] [email protected] 26 points 1 year ago (4 children)

Every shot and booster I've had made me feel like shit for several days, and made my arm throb as if I'd been shot for about a week.

But if my choice is between that and long covid, well, I'm chosing the shot lol.

[–] [email protected] 19 points 1 year ago

But if my choice is between that and long covid, well, I’m chosing the shot lol.

Bingo. I have extended family with long COVID and it sucks ass. My father-in-law used to be the strongest and most active guy I knew. Woodland firefighter, constantly doing stuff with his hands. All of that is over now. Long COVID has wrecked him. He's probably going to be on supplemental oxygen for the rest of his life.

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[–] [email protected] 10 points 1 year ago (1 children)

Oddly enough, none of the COVID vaccines or boosters have affected me in any significant way... but... I got my flu shot last week and it hit me like a freight train. I was having to fight to speak clearly in a work meeting thirty minutes after the injection, but on the plus side, it's nice to know my body's building an immune response.

[–] [email protected] 3 points 1 year ago

I'm glad someone else has an immune system that doesn't hate them, I'm going in later this week and this crowd was making me feel anxious even though I've never had a reaction to vaccines.

[–] [email protected] 9 points 1 year ago

Your experience matches every shot I’ve had with Moderna. I’m planning to get Pfizer this time around, in the hopes that it goes easier on my body 🤞

[–] [email protected] 8 points 1 year ago (2 children)

The old Pfizer doses would shut me down for 3 days.

Fever, chills, body aches, fatigue.

The first shot wasn't so bad. The second and third were insane.

I'm pretty sure I've had a fourth shot, but I don't remember how I felt. I think I got covid last year, after already having the third shot, and I've been dealing with symptoms for over a year now (mostly muscle fatigue).

I want the new shot with the new variant mix, but I'm also afraid of how I'm going to react to it. I have too much going on at work and home right now to take half a week off for the shot.

I have a pretty crummy immune system and have always dealt with autoimmune issues, so it's important that I get the shot, even if I react badly to it. :/

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[–] [email protected] 8 points 1 year ago

According to my records i've had Pfizer and Moderna vaccines. Apart from a sore arm and maybe a bit tired, i thankfully had no other symptoms.

[–] [email protected] 8 points 1 year ago (1 children)

I think it’s good if you have a strong immune system response to the vax. It means your immune system will be charged up with antibodies.

I always plan to take 1-2 days off after getting vaccinated.

[–] [email protected] 3 points 1 year ago

That's what I should have done. Oh well. At least I'm feeling a lot better this morning. C'est la vie.

[–] [email protected] 7 points 1 year ago

Haven't gotten the new vaccine yet, but my first moderna gave me some chills, headache, and fatigue, I didn't check my temperature but I wouldn't have been surprised if I had a slight fever. It hit me maybe 8-12 ish hours after I got it, not too bad, but not exactly fun either, could have worked through it if I needed to but I was glad I had the day off. The real kicker for me though was I work night shift, I got it right after work in the morning, went home, went to bed, and it started hitting me a bit after I got up the next evening, and by the time I was ready to go to sleep the next morning I was feeling fine. If I'd been on a normal schedule and got the vaccine at the same time, I probably would have been going to bed at about the same time it hit me and I would have slept through all of the symptoms.

Most of my boosters have been moderna, and I haven't had any issues with them besides a sore arm, so I think the first dose was my immune system going "hey wait, what the fuck is this? We got a code red over here" And with the boosters it pretty much just went "oh, ok, another one of these, go ahead and put it with the others, no biggie"

The one Pfizer vaccine I did get didn't seem to make my arm quite as sore as the others. So that's something I guess.

[–] [email protected] 7 points 1 year ago (1 children)

So interesting to hear all of the individual reactions. I had the Pfizer primary series - the first shot was rough but the second shot, and the Moderna booster I had later, only caused some arm pain.

I just had my fourth shot, the Moderna Spikefax, along with the flu shot at the same time. Caused malaise overnight and pain in the COVID shot location for 3 days.

Whatever pain and inconvenience the vaccine shots cause it's nothing like having COVID. Ask me how I know.

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[–] [email protected] 7 points 1 year ago

Normal. After I took it, I was feeling like I’d done an intense all body workout, like all my muscles felt sore. Was basically done the next day.

[–] [email protected] 6 points 1 year ago

When I took the Moderna two dose in 2021, I was stuck in bed having fever dreams for a couple of days. Like I was hallucinating that I was in different places. Sickest I’ve ever been in my life.

[–] [email protected] 6 points 1 year ago

Guess I've been lucky. The first vaccine I got (which was Pfizer) made me a bit sick for a couple of days with a brutally sore arm. Since then, every booster I've gotten (Pfizer and Moderna) has just given me a sore arm for a few days. I usually get cold-like symptoms after I get a flu shot, so I guess the Covid shots aren't as hard on me somehow.

[–] [email protected] 6 points 1 year ago

Don't think I had any fever today but definitely fatigued, sore, body aches, and chills last night (vaccinated yesterday + flu). Had moderna for shots 1 & 2, and Pfizer for 3 (no real side effects I can remember). Wasn't expecting to have any side effects since they were very mild after booster 2, but definitely was wrong. Wanted to try Novavax but don't think it's been approved yet and didn't want to wait any longer

[–] [email protected] 5 points 1 year ago (1 children)

It's well known Moderna boosters to have the most side effects like the ones you describe. I hope you're doing okay, now.

[–] [email protected] 6 points 1 year ago

Much, much better today. Like a switch was flipped. Basically feeling fine.

[–] [email protected] 5 points 1 year ago (1 children)

Moderna was the easiest on me - did not feel a thing, not even a shoulder pain. I guess this is individual.

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[–] [email protected] 5 points 1 year ago

Actually the old Moderna was having such a harsh reaction on younger people, Germany changed their recommendations to not allow anyone younger than 60 to get moderna.

I also had Moderna back then once and can only confirm, it knocked me completely out for a whole day with harsh fever like symptoms, really wasn't fun.

Haven't really been vaccinated for a year now, so can't talk about the new moderna.

[–] [email protected] 5 points 1 year ago

Yep, did that this past weekend. Not a whole hell of a lot of fun. Advil helps a lot with the fever and chills.

[–] [email protected] 5 points 1 year ago* (last edited 1 year ago) (1 children)

I really just get muscle ache and chills really bad. It lasts a day or two for me at most. What's weird is when I got my last booster of Pfizer a few months ago, I got a dtap (the giga vaccine) in both my arms at the same time and had zero sickness the next day lol. Then I took the flu vaccine and still got sick a few weeks later so I feel scammed.

Also just remember, the covid vaccine doesn't stop the spread, that is misinformation. It greatly improved your immunization towards it so you don't get nearly as sick.

[–] [email protected] 7 points 1 year ago

Also just remember, the covid vaccine doesn’t stop the spread, that is misinformation. It greatly improved your immunization towards it so you don’t get nearly as sick.

It doesn't stop the spread, but it reduces it. If you are infected when vaccinated, your illness will likely be much shorter, which means much less time during which you're contagious. So the vaccines are still very important for slowing down the virus, even if you aren't guaranteed full immunity.

[–] [email protected] 4 points 1 year ago

I got the latest Pfizer and it knocked me out for about a day. Extreme fatigue, chills, and sore muscles all over kicked in about 10 hours after the shot, lasted about 6 hours, and then I slept after that.

[–] [email protected] 4 points 1 year ago

Each of mine has been Pfizer but the stories I've heard about Moderna are consistent with yours

[–] [email protected] 4 points 1 year ago* (last edited 1 year ago) (1 children)

First shot of the Moderna vaccine I was not doing bad, bit tired for a week but nothing else really note worthy.

But the day after my second shot I woke up to heavy chest and heart pains. I didn't know what was the matter, my first thought was: "am I having a heart attack?!"

Couldn't move and hardly breath from pain, it took over a half hour before I could finally grab my phone and call my house doctor's office. I explained what was going on and that I had my shot the day prior. Was being told that was just a side effect from the shots and that just should take painkillers and try to tough it out. If it wasn't going any better in a day or two I should call back to make a appointment.

After a short half day a couldn't take it anymore, called my doctor back and he told me to go to the hospital.

Luckily I could come the same day and they did multiple tests. Had to stay the night because the results wouldn't be ready till the next day.

Well it turned out that had a inflamed heart muscle pouch, had to translate. Hope it's correct.

Stayed in the hospital for almost 3 weeks. I got oxygen, because I had trouble breathing and I got all I kinds of drugs all day long to help me out.

After that they said I could go home but call right away when there was any problems.

I couldn't work for almost three months and during that time went back to the hospital 2 times because returning heavy pains on my chest.

After those three months I figured it's time to go back to work but only like 2 or 3 days per week to start with because I still had breathing problems and sometimes the pain would come back.

I'm doing better but still sometimes I have trouble breathing and have to take it easy.

I didn't even wanted to get the shots but had to because of my work.

[–] [email protected] 6 points 1 year ago

I'm sorry that happened, but you must know reactions like that are extraordinarily rare, and COVID-19 itself frequently causes much more severe heart injury.

I hope you're doing better now.

[–] [email protected] 3 points 1 year ago (1 children)

Sounds about right. Haven't gotten the updated shot yet but I've gotten the first Moderna shot & later the Moderna booster. Both times I kind of went through a quick and short fever/chills stage & some fatigue.

For me personally that seems to kick in around 8-12 hours after the shot so I try to get it early in the day, head to work/head home, then with any luck I sleep through most of the side effects & feel more or less okay the next day.

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[–] [email protected] 3 points 1 year ago

I had a very similar experience the first time I had a Pfizer shot, I think it's fairly common

[–] [email protected] 3 points 1 year ago

This was my experience with the initial rounds, but I was very happy to not get COVID. My employer gave me time off for recovery just from the vaccine which was great so I just didn't do anything for a day.

I'm still waiting for my new shot now. Seems like all the pharmacies are backed up by a week or more, but I should be getting another Moderna next week.

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