One time a woman told me that my lack of a second X Chromosome meant I would "always be a man"
So I gaslit her into thinking her husband had klinefelters.
I hate how Republicans think transphobia is science
A place for majestic STEMLORD peacocking, as well as memes about the realities of working in a lab.
Rules
This is a science community. We use the Dawkins definition of meme.
One time a woman told me that my lack of a second X Chromosome meant I would "always be a man"
So I gaslit her into thinking her husband had klinefelters.
I hate how Republicans think transphobia is science
"Yeah but science can be proven wrong an change over time, while my beliefs and biases are forever!"
Wait until they learn about XXY, XYY, and XO individuals.
I swear I was learning about extra X and Y in high school 20 years ago and that studies (at the time) were showing correlation between different traits displayed by effected people. Just that alone shows incredible gender fluidity.
So where we are, 20 years later, you’d think we’d have a better understanding within society but instead somehow it’s literally regressed since then.
I hope this criticism is valid :
https://economicsfromthetopdown.com/2022/04/08/the-dunning-kruger-effect-is-autocorrelation/
and
https://www.realclearscience.com/articles/2023/05/09/debunking_the_dunning-kruger_effect_898340.html#!
...
There is a "people think they are better than average" rule, rather than whatever Dunning-Kreuger suggested.
While this is very funny, and definitely representative of a sort of ignorance/arrogance commonly found in ideologues - I recently learned that most people talking about the effect have, in fact, been Dunning-Krugering themselves.
Insightful video on the topic.
What most people expect the effect to look like:
What the actual results were:
Can I get a T shirt that says “I have Dunning-Krueger and your Phd looks cute”? I just have a lot of BS to share and I don’t want to be sorry about it.
You know how a bunch of villains are Dr. So-and-So? I bet it's dealing with morons talking about your area of expertise that leads to one's villain era.
Can someone explain to me how some XX people become cis male?
https://en.wikipedia.org/wiki/XX_male_syndrome
tldr biology is dice rolls and humans are intersex for no reason sometimes
on a side note one of my friends had this and she only found out when she started transitioning. she is now a trans woman with XX chromosomes. i can only imagine how fucking vindicating it must have felt
De La Chappell syndrome, congenital adrenal hyperplasia, androgen exposure in utero, ovotesticular disorder of of sex development all result in a person with cis male characteristics and in some cases cis male typical genitalia despite having xx chromosomes
Gene expression is not as straightforward as people think. All sorts of weird shit can happen, and that's not even including gene mutations.
https://static.scientificamerican.com/sciam/assets/File/Pitch_sketch_final.png?w=2000
This is the best resource I've seen to show things relatively simply.
The TL;DR is that a whole "Y" chromosome isn't exactly responsible for "maleness", the SRY gene is. It's normally on the Y chromosome, but mutations can occur placing that gene onto the X chromosome. Inversely, someone could inherit a Y chromosome without that gene, in which case they would develop with female traits.
It's not considered trans because someone with 46XX plus the SRY gene would develop male genitalia, be identified as male at birth, and likely identify themselves as male. For some types of these conditions, there are plenty of people walking around with no clue that their chromosomes don't match their gender.
Disclaimer: I'm not a geneticist, so i could have explained something a little off.