It's been a little while since I've printed anything that needed specific settings like this, but I'm pretty sure that Cura's combing/ avoid printed areas settings will do this for you. Though I don't have any experience with one wall thickness parts and this setting.
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Interesting, Cura does successfully avoid running into the part by default:
If I disable "Avoid Printed Parts When Traveling", the result looks similar to PrusaSlicer.
I think the issue is with it being just a single wall. The slicer tends to have some trouble with that.
My first thought was just to model the return paths as well, making it a loop, print that in vase mode, then just cut away the unwanted parts. My second thought was to wonder whether there would be a way to use post-processing to set the extrusion to zero for those particular paths, maybe using the multicolor features, and thereby avoid printing the extra area.
@p1mrx you could try making the seam in the middle of the part. It won't cross but will still have to travel. Vase mode would work if it was two wide!