I am a massive Distrobox fan. I do not use it for security though.
- create environments for specific purposes: dev, testing, cybersecurity work, video, AI, etc
- access to the full app library of any distro
- isolation of multiple large apps for easy and complete removal when you are done with them
- use Glibc apps on your MUSL distro
- install apps easily on an immutable distro
- total compatibility ( eg. Legally install a real RHEL9 Distrobox for free )
- ”try out” an unfamiliar distro without a VM
- experiment and break things without messing up your main system
- separate your distro base from your userland ( eg. Minimal Debian Stable install with pretty much all apps coming from an Arch Linux Distrobox ). Rock solid stability of the base system paired with a massive ecosystem of up-to-date packages.