What are you into? Lake Merritt, Jack London Square, and Uptown are common options.
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Thank you for the information.
For me I think I would check out Yoshi's, the Planetarium, and the Foundry.
However, I will be there with a friend. Together we typically check out things like botanical gardens, eclectic shops, and baseball. Unfortunately, the A's won't be playing while we are there. Lake Merritt seems like a good choice. What are the vibes like at Jack London Square and Uptown?
Uptown was the go-to place for bars and going out (at least before the pandemic), and Jack London Square is mostly new development with a lot of nice restaurants and breweries. It's also near the water, so it's pretty nice.
Honestly though, if you're into eclectic, Piedmont Avenue and Temescal has a more neighbor-y and local feel. But even better may be to take the BART a few stops or drive to Berkeley, which definitely has a more unique and eclectic feel. Even better, Berkeley has a pretty nice botanical garden.