spoiler
It seems like this Miles-42 is open about being the Prowler since he doesn't hide his designs from his mom. We also know that the spiders bite beings that are "good". If the spider was going to bite Miles-42 then that means we might see a team up of these two instead of a fight.
...or he might blame Miles-1610 like Miguel did ๐
Spider-Totems aren't necessarily good. Look at the many different evil spider-men in the marvel multiverse.