I think there is a difference.

Basically all animals will attack other animals when they invade their home space. Even insects do so and it can be brutal. Speaking outside of human moral constructs, you wouldn't be out of line for killing a rat or even a cat that was unwelcome in your home. Life will do what it can to ensure survival.

But it's easier to feel empathy for what is more similar to us. So, mammals, for example. Domesticated and tame animals that have adapted to humans.

I suggest making small efforts to cultivate compassion even for the creepiest insects, by taking a cup, bowl, or piece of paper and taking them outside. Now it could be argued whether this is doing them any favors, but I feel better about that compared to just smashing them.

It may sound ridiculous but yes I did reach the point where I am affected by any life I take, and really strive to avoid it where possible. I have "mutual arrangements" with a variety of insects in my house, such as small spiders. They stay out of my way, and I let them take care of other insects that slip through the cracks.