this post was submitted on 25 Sep 2023
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I buy these things but I wonder if they are truly pharmacologically-active and not just bullshit. Discuss

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[–] [email protected] 19 points 1 year ago (3 children)

In case I'm perceived as biased or part of BigAntiCalmingTea, I'm consuming a cup right now...

[–] [email protected] 11 points 1 year ago (1 children)

Have you tried the enema method?

[–] [email protected] 15 points 1 year ago* (last edited 1 year ago) (2 children)

No comment (;) [butthole wink]

[–] [email protected] 6 points 1 year ago (1 children)

Are you a the Snow Plow Show fan or are butthole winks from something else I don't know about?

[–] [email protected] 4 points 1 year ago* (last edited 1 year ago) (1 children)

I have no idea. I was just riffing ;)

[–] [email protected] 5 points 1 year ago (1 children)

Riffing. There's a word used far too little, I hope I remember it later so I can use it later. 'joking around', 'kidding' 'just joshing'... I need more riffing in my life.

[–] [email protected] 3 points 1 year ago

See Robin Williams

[–] [email protected] 5 points 1 year ago

My b-hole winked when I read this.

[–] [email protected] 8 points 1 year ago (1 children)

Everyone's biochemistry is different, that's why we had the opioid epidemic and not an opioid pandemic...

It might work on others, but not you. And for a decent amount of people it works for, a significant amount are having the placebo effect.

So just go into it with an open mind thinking it may relax you, and it might. Even though I've just told you it could be placebo, that doesn't hurt it's chances. (Crazy side note: the opposite of a placebo is a nocebo, something that gives a negative effect. Being aware of that does prevent it).

If you do it for a while, simply the act of putting a kettle on would have you relaxed before you've taken a drink. It doesn't matter why it works, just that it does.

[–] [email protected] 3 points 1 year ago* (last edited 1 year ago) (2 children)

that's why we had the opioid epidemic and not an opioid pandemic...

Maybe. But I think there are also just a lot of people that are not dealing with enough trauma and mental pain (pain-killers/type not specific) that their inner voice stops them from seeking it out.

My dad had a friend with brain cancer. He was in hospice many years ago and knew that I had struggled with addiction. He said he had received hydrocodone and oxycodone after surgeries before (he'd had many) but they always made him nauseous and feel like shit. Then at the end when he was in hospice they gave him a fentanyl patch. He said "MyName, WOW, I FINALLY UNDERSTAND how people can get addicted to this stuff now. This is remarkable!"

Off-topic story: shortly after he passed I was looking for ways to painlessly "catch the bus" on the internet (I'm fine now, this was many moons ago) and bawling my eyes out as I thought about my family and what I'd be putting them through. Suddenly, the piano next to me blasted as if someone had pounded 10 of the keys at once as hard as they possibly could. No pets, no other people home.

I've been through a lot since then and am happy to say I am doing fine now, but that's one of those many WTF moments that turned me from a staunch materialistic atheist into a more spiritually understanding person.

That and the DMT. Only slightly riffing, DMT came way before that.

[–] [email protected] 3 points 1 year ago

There's a convention or interpolation wirh regard to opioids/opiates such that:

  1. 1/3 hate it (side effects)
  2. 1/3 are neutral (it attenuates their physical pain and nothing else
  3. 1/3 LOVE. IT. (euphoria, complacency, acceptance of otherwise intolerable contexts)
[–] [email protected] 2 points 1 year ago (1 children)

Well, yeah...

Your first example needs metabolized into an active ingredient. The second is an active ingredient.

There's a bunch of different liver enzymes at play, and an absolute shit ton of normal variation between people.

Too much of those enzymes, and you burn through a 12 hr oxy in 6 hours, which makes people likely to abuse their own medication and can lead to life long addicts.

Too little and you get zero effect from "normal" opioids, but fentanyl, morphine, and other direct action opioids stick around for a lot longer and you have no tolerance.

That's what I'm saying:

Everyone’s biochemistry is different,

[–] [email protected] 2 points 1 year ago

Yes I was just sharing a side-thought while agreeing and sharing a story.

[–] [email protected] 6 points 1 year ago (1 children)

Not gonna lie, I'm kinda tempted to start a line of rage-inducing Anti-Calming teas...Maybe ephedra or some shit