this post was submitted on 22 Sep 2023
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Neuralink’s human trials volunteers ‘should have serious concerns,’ say medical experts::A medical ethics committee responded to Elon Musk's brain-interface startup issuing an open call for patients yesterday.

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[–] [email protected] 83 points 11 months ago (1 children)

Yeah, I mean we've been working on brain implants of various stripes for a couple decades now, and they're not the first to attempt motor cortex implants for paralyzed patients as a method to begin human trials, but the current state of the art for brain implants is honestly pretty... primitive. There's no good way to avoid damaging neurons, so it's mainly a focus on not causing too much damage while fine mapping and targeting has to be done on an individual basis.

Implants are hugely useful, and arguably the current state of the art treatment for several conditions (epilepsy and parkinsons), but we're so far out from computer brain interfaces being useful for anything outside of dire medical needs that it's kinda surprising they're pushing ahead when they had so much trouble with their experimental subjects.

I worked in a brain imaging lab in college, and we had a couple of chimpanzees with brain implants that did daily research protocols. Bastards were better than me at the testing regimen, and other than some minor discomfort (water intake is restricted prior to the tests so that the gatorade reward was more attractive), they were large children that could tear your face off if they got angry. Once they got older, they would have surgery to remove the implants and retire to a primate ranch where they just got to live out the rest of their life. All of the grad students there had been working with the same chimps for years, so it's a little alarming Neuralink had so many issues.

It doesn't exactly engender confidence.

[–] [email protected] 40 points 11 months ago (2 children)

What's really sad is hearing how they treated them. Considering how intelligent they are, I find it disgusting that they treated them so bad they all died. It's not worth a bunch of sentient creatures lives to do experiments like this and then just throw them away.

At least your lab was treating them with dignity.

[–] [email protected] 27 points 11 months ago

Yeah, in academia getting approval for primate research projects is a huge process where you need to clarify every aspect of the protocol, housing, care, and experimental operations to submit before the project can start. I'm less sure if it's voluntary or required, but we had funding allocated for their retirement from the start. They're smart enough and strong enough that I'd be terrified to work with unhappy and unwell primates.

Not that all research projects are have happy endings, but I don't think corporate research has the same restrictions and oversight that academic research does, given that this even happened. I'm pretty accepting of the necessity of primate research models, but we should be doing everything we can to treat them as best we can. Withdrawing a subject from the experimental protocol should be preferred over letting an infection fester just because the implant is in the way. Just seems really poorly done on their part.

[–] [email protected] 7 points 11 months ago (1 children)

If it makes you feel any better, they'd treat humans the same way if they could.

[–] [email protected] 2 points 11 months ago

Not really. I know people have done some crazy despicable experiments during wartime, so not surprising people are willing to do it if allowed.