this post was submitted on 16 Oct 2024
1047 points (99.3% liked)

Science Memes

11205 readers
2614 users here now

Welcome to c/science_memes @ Mander.xyz!

A place for majestic STEMLORD peacocking, as well as memes about the realities of working in a lab.

Rules

  1. Don't throw mud. Behave like an intellectual and remember the human.
  2. Keep it rooted (on topic).
  3. No spam.
  4. Infographics welcome, get schooled.

This is a science community. We use the Dawkins definition of meme.

Research Committee

Other Mander Communities

Science and Research

Biology and Life Sciences

Physical Sciences

Humanities and Social Sciences

Practical and Applied Sciences

Memes

Miscellaneous

founded 2 years ago
MODERATORS
[email protected]
[email protected]
[email protected]
1047
Hmmmm (mander.xyz)
submitted 1 month ago by [email protected] to c/[email protected]
78 comments fedilink hide all child comments
 
you are viewing a single comment's thread
view the rest of the comments
[–] [email protected] 17 points 1 month ago (4 children)

I'm currently writing a small literature review on tgf-b and SMAD signalling in cancer for uni rn

And I'm really confused why this one paper's talking about how miR-520h induces the tgf-b/smad7 pathway but also binds to and suppresses smad7

Like why on earth is it activating the tgf-b/smad7 pathway, a pathway that stops stuff like the epithelial mesenchynal transition, if it's just going to bind to smad7 anyway???

Worst thing is, I can't find any other papers on why this actually happens

I swear I'm just dumb at times ;-;

[–] [email protected] 17 points 1 month ago (1 children)

[–] [email protected] 1 points 1 month ago

I'll take two scoops

[–] [email protected] 8 points 1 month ago

Ah, yes. Of course. I understand your frustration entirely because of my deep understanding of the specific situation.

[–] [email protected] 5 points 1 month ago (1 children)

Would a list of tools and search engines be helpful?

[–] [email protected] 1 points 1 month ago (1 children)

That would be very helpful 🥴

[–] [email protected] 2 points 4 weeks ago

Sorry, better late than never. Will dm you. Others are welcome too.

[–] [email protected] 4 points 1 month ago

Cell signalling pathways was the worst part of microbial genetics for me. Luckily I don't have to deal with that anymore as my day to day is digital PCR and NGS.