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Depends on what you want to take them for.
Most fish oil is completely ineffective:
https://health.clevelandclinic.org/fish-oil
https://www.health.harvard.edu/heart-health/the-false-promise-of-fish-oil-supplements
Some medications can cause a CoQ10 deficiency, so if you're on one of those medications, you might need a supplement, but absent that, there's no reason to take fish oil.
I've personally noticed some powerful effects from fish oil: 1) it can act as a neotropic booster, particularly in conjunction with SRI's and similar meds / substances, 2) it can cause me significant insomnia (no arrhythmia) if I take ~6-8 capsules.
Is that germane to this thread? Probably not, but something seems to be going on. Maybe fish oil has been studied so far on too limited a basis.
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I guess I should have said "ineffective for the various health claims". Anything can have an effect if taken in large enough doses. :)
https://www.medicalnewstoday.com/articles/318619
The other point I want to throw out there is that Omega 3 is essential, it cannot be endogenously provisioned, and I'm not sold that ALA sufficiently stands in for EPA and DHA
Understood; just wanted to add on.
My point is more or less that this doesn't have to be a closed-book situation about fish oil. Maybe it can help in some other way, and/or maybe it really can work as 'advertised' in conjunction with other substances. Certainly wouldn't be the first time, if so.