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World-first lung cancer vaccine trials launched across seven countries (www.theguardian.com)

submitted 4 months ago* (last edited 4 months ago) by [email protected] to c/[email protected]

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Doctors have begun trialling the world’s first mRNA lung cancer vaccine in patients, as experts hailed its “groundbreaking” potential to save thousands of lives.

Lung cancer is the world’s leading cause of cancer death, accounting for about 1.8m deaths every year. Survival rates in those with advanced forms of the disease, where tumours have spread, are particularly poor.

Now experts are testing a new jab that instructs the body to hunt down and kill cancer cells – then prevents them ever coming back. Known as BNT116 and made by BioNTech, the vaccine is designed to treat non-small cell lung cancer (NSCLC), the most common form of the disease.

The phase 1 clinical trial, the first human study of BNT116, has launched across 34 research sites in seven countries: the UK, US, Germany, Hungary, Poland, Spain and Turkey.

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[–] nkat2112 22 points 4 months ago

This is wonderful news! And nice to see BioNTech's use of mRNA moving forward! Let's hope things work out well and that they're able to make it work for other cancers too at some point.