Nope! Just decided to be a disappearing asshole for 36 hours and come back like nothing happened.
edit: thanks to all for the different perspectives. he is fixed, has all of his shots, and has his own temperature contolled kitty condo (aka the laundry room) that we put him into every night. we have a pretty good network of neighbors and pieced together his activities via security cameras. he's a mouser for sure and that is his job until he decides to retire.
To add on, cats have contributed to many many species extinction. Here are some examples just from Australia alone.