this post was submitted on 27 Jun 2023
1 points (100.0% liked)

Biotechnology

10 readers
1 users here now

Biology and technology to tackle the issues of the 21st century.

founded 1 year ago
MODERATORS
 

I haven't editorialized the title, but I don't like it since the desired protein structure was thought up by the grad student and the "digitally designed" piece just seems to be some MD modelling to confirm the desired outcome before synthesis.

That being said, I thought this was interesting since freeze/thaw (F/T) stress is ubiquitous in the life sciences and something that is especially important to the emerging field of cell therapy. Typically, excipients like sucrose, trehalose, or glycerol are used to preserve biological molecules during F/T, but they are not protective in every case. Developing alternative means to protect during F/T gives people like me that develop therapeutic formulations more options to turn to in the case of difficult molecules.

doi: https://dx.doi.org/10.1073/pnas.2220380120

no comments (yet)
sorted by: hot top controversial new old
there doesn't seem to be anything here