Fully upgraded uranium tank rounds kill them pretty fast. Just make sure to stay away from explosive ammo

You're not using enough nuke.

Am I the only one who's not had a problem with just using basic turrets to wipe them out in 5 seconds? Made entirely from free resources on Vulc, the only cost is bot attrition from the dust cloud.

But they can? One nuke to the head works for small. Two works for medium. I haven't come across a large yet.

Railguns, right down their gullet. Basically the only reason to make the personal ones, but damn if they aren’t good at what they do.

I set up 10 - 20 artillery cannons, 5 shells each, and spammed it until it went down.

Likely a bit over kill, worked for small and medium, haven't don't large yet

You can one-shot a medium worm with an epic quality railgun round. Large worms require about ten epic railgun rounds