Currently only supports WebKit and Blink (experimental) as underlying browser renderers. The description of the browser starting with the words "Nyxt is a browser with deeply integrated AI [...]" is a turn-off for me. If it is for powerusers, call it what it is. It could be a LLM or some algorithm, idk.
I may check it in a year. For now, for Blink (Chromium) engine use Cromite browser + uBlock Origin Lite, for Gecko (Firefox) use Librewolf or Mullvad browsers.
The browser app is the only program where (to me) Security/Privacy fully supersedes any concerns customizability and usability.