Chronic Illness

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Pony Rule (lemmy.world)

submitted 1 month ago by [email protected] to c/[email protected]

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[–] [email protected] 14 points 1 month ago (2 children)

I haven't had a migraine free day in at least 4 years. I have tried every migraine drug on the market. The only thing that works for me is Midrin. Which was discontinued in 2009. Good thing you can get it at a compounding pharmacy. Oh wait! You can't anymore. You can't get it anywhere. This last bottle on my desk is evidently one of the last in existence. And it's the only thing that works. So no, I won't just be taking the headache medicine. I've got to save it for when I have to function, not for when I want to feel better.

[–] [email protected] 5 points 1 month ago

Have you seen this article? It gives you the component breakdown so you can try to find the 3 drugs that make it up, or you can try the alternative that has 2/3 of the drugs that is still on the market.

[–] [email protected] 4 points 1 month ago (1 children)

Hmm, Wikipedia tells me:

However, it is now being manufactured by Macoven Pharmaceuticals and marketed under the name Nodolor, as of April 2014.

https://en.wikipedia.org/wiki/Amidrine

[–] [email protected] 5 points 1 month ago (1 children)

Yeah, I know (I checked it before I posted on the off chance I'd find some good news). That page hasn't been updated in a while and I was only told there would be no more available back in April

[–] [email protected] 3 points 1 month ago

Ah ok, that's unfortunate...

[–] [email protected] 10 points 1 month ago

... and a full glass of water.

[–] [email protected] 2 points 1 month ago (1 children)

I can make things easier for myself and I should, all my hunter-gatherer ancestors agree and they're the only ones that matter.

[–] [email protected] 1 points 1 month ago (2 children)

Is it more that we don't hear about the hunter-gatherer ancestors that died by making things themselves due to survivorship bias?

[–] [email protected] 2 points 1 month ago

That's a fallacy. Individuals don't evolve, and neither do whole species; it's populations that evolve, which for humans means tribes. Behaviours that help the tribe's survival mean the whole tribe is favoured, even if the individuals exhibiting those behaviours never reproduce themselves. Why do you think latent genes are a thing? How do you think humans developed things like altruism?

[–] [email protected] 1 points 1 month ago

I don't know, my hunter-gatherer ancestors hate me because I have no kids.

We have a tumultuous relationship.

[–] [email protected] 2 points 1 month ago (1 children)

Problem is, I often have pain, so I try to do all I can to reduce the already significant amount of ibuprofen I use.

[–] [email protected] 3 points 1 month ago (1 children)

You gotta step up to naproxen, bro. Just make sure you eat something with each dose or it will fuck up your stomach.

[–] [email protected] 0 points 1 month ago* (last edited 1 month ago)

They're both bad long term.

NSAIDS are indiscriminate COX inhibitors (which is why they mess with your stomach, COX-1 is part of the stomach lining goo production). COX-2 inhibitors such as Celebrex don't have this issue (or at least significantly less).

Personally I don't find any of the COX inhibitors to be effective at all, and their risks are well above 0.

Makes me wonder if other, supposedly "risky" drugs are actually a better choice.