I'm surprised. As I understand it, the Alzheimer's field is starting to recognize that the plaques are likely a result of, rather than a cause of, the disease. And that the cause may be more related to a, potentially microglia related, inflammatory problem in the CNS
this post was submitted on 01 Jun 2024
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There are sort of two paths in the research. Some are following the Amyloid Plaque route still. There was a bit of kerfuffle with some of the evidence in other studies which was the basis of this route: https://www.science.org/content/article/potential-fabrication-research-images-threatens-key-theory-alzheimers-disease
Once you're too far down one path of research, you pretty much can't stop, or you risk your entire career, evidence be damned.
Thanks, that was a good read. It is terrible that some researchers end up committing such scientific fraud. Although I am inclined to blame the involved researchers themselves, ultimately, I believe that inflexible (and insufficient) funding is the real culprit
I suspect both methods will be necessary. Step A - clean up amyloid. Step B stop excess amyloid production.