A Warhammer+Freehand setup is a pretty good baseline. Prone + Grabbed is a nasty debuff combo, and you can inflict the first condition with Hammer crit spec, and the second from Combat Grab from lv 2 Fighter. Beyond that, you're kind of free to explore any build paths however you please.
You could grab a spiked gauntlet and pairing rings to make Combat grabs more accurate.
You could invest into some handwraps of mighty blows and go hard into wrestler for the special moves that require unarmed strikes.
You could dip into some spellcasting archetypes for Enlarge so that you can grapple huge creatures.