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Molise it's a meme in Italy for it's irrelevance to the Italian landscape (be it political, cultural,sportive,...) and people meme it doesn't exist and that it's actually fictional like Atlantis and similar fake regions

Trentino-Alto Adige is the part of Italy that includes South Tyrol and athletes there are more focused on winter sports, some exceptions exist (Sinner with tennis but even him was a grand slalom winner before choosing tennis over skiing) but are rare.

Valle d'Aosta is a fully mountainous region (between France and Switzerland) and has the lowest population in Italy because of its size and rurality. Athletes are rare and like Trentino usually going to practice winter sports instead of footbal.