So hopefully I'm doing this right! :) (I'm still new to some of this so haven't figured out things yet! I did ask this via Mastodon also, but wanted to add more detail to my answer!)
Is there a computer game, a moment in a game, a boss fight, or a specific moment that you would love to experience fresh with no prior memory of it?
Mine would have to be The Seat of Sacrifice fight in Final Fantasy XIV, one of if not my most favourite fights in the game to date.
The mechanics work so well and tie into everything that's been happening, and then that moment where <redacted> (I refuse to spoil it!) shows up to help and then leaves with I think what made me cheer SO MUCH the first time I did the fight.
The music, the song To The Edge has become one of my most played songs in my entire music library (alongside Endwalker - Footfalls and Shadowbringers) as it is quite frankly perfect for the fight. and when they revealed that Soken had been battling cancer and wrote it whilst in hospital...
I adore the fight all together, and cannot help but say the lines in the cut scene bit in the middle every time I do the fight, and will never ever get bored of it.
So what moments in a game would you love to complete again with no prior experience?
Ok, somehow I've missed The Outer Wilds. And I've played like nearly everything else people have mentioned. But since this is far and away the most mentioned game here, sounds like I need to play it :)
It's a game where all of the progression is knowledge based. So once you play through the whole thing once, it'll never really be the same again. Absolutely loved my time in it. I never thought they'd be able to do that twice, but the DLC effectively hit me all over again. I highly recommend that, too. Play it and tell me what you think once you're done!