this post was submitted on 15 Jul 2024
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Chronic Illness

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[–] [email protected] 2 points 1 month ago (2 children)

Problem is, I often have pain, so I try to do all I can to reduce the already significant amount of ibuprofen I use.

[–] [email protected] 3 points 1 month ago (1 children)

You gotta step up to naproxen, bro. Just make sure you eat something with each dose or it will fuck up your stomach.

[–] [email protected] 0 points 1 month ago* (last edited 1 month ago)

They're both bad long term.

NSAIDS are indiscriminate COX inhibitors (which is why they mess with your stomach, COX-1 is part of the stomach lining goo production). COX-2 inhibitors such as Celebrex don't have this issue (or at least significantly less).

Personally I don't find any of the COX inhibitors to be effective at all, and their risks are well above 0.

Makes me wonder if other, supposedly "risky" drugs are actually a better choice.