this post was submitted on 15 Nov 2023
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[–] [email protected] 1 points 11 months ago (7 children)

I've been on a million medications for a million things, I get some fairly bad side effects sometimes but it's almost always physical, and I've never had side effects from a painkiller before this, and I don't know how unusual this is, but on tramadol I had the wildest mood swings of my life. I was on holiday when taking it, and I don't know if I took too much or another medication fucked with it, but one minute I was doing what my mate called a "frog dance" in the pool in complete bliss laughing my head off, then I was angrier than I've ever been, then I was incredibly depressed in a very short space of time where literally nothing happened to cause any of it. I'd never experienced anything like it, it was horrible and I never want to take it again.

[–] [email protected] 1 points 11 months ago

Tramadol also acts as an SNRI (similar to antidepressants cymbalta and Effexor) in addition to acting on opioid receptors. Might be why it felt odd.

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